Early diagnosis of tuberculous meningitis: A comparison of nested polymerase chain reaction and BacT/ALERT
نویسندگان
چکیده
منابع مشابه
EVALUATION OF DIRECT MICROSCOPY, CULTURE, AND POLYMERASE CHAIN REACTION FOR THE DIAGNOSIS OF TUBERCULOUS MENINGITIS
In view of the importance of early diagnosis of tuberculous meningitis (TBM), the efficiency of the polymerase chain reaction (PCR), one of the most reliable and sensitive DNA-based assays, was compared with conventional methods (acid-fast microscopy and culture) for the detection of M. tuberculosis in cerebrospinal fluid (CSF) specimens from patients suspected of TBM. Of the 29 CSF specim...
متن کاملevaluation of direct microscopy, culture, and polymerase chain reaction for the diagnosis of tuberculous meningitis
in view of the importance of early diagnosis of tuberculous meningitis (tbm), the efficiency of the polymerase chain reaction (pcr), one of the most reliable and sensitive dna-based assays, was compared with conventional methods (acid-fast microscopy and culture) for the detection of m. tuberculosis in cerebrospinal fluid (csf) specimens from patients suspected of tbm. of the 29 csf specimens f...
متن کاملA Study of Polymerase Chain Reaction in Cerebrospinal Fluid for Diagnosis of Tuberculous Meningitis
Methods: All children having CNS illness and undergoing CSF examination were included in the study and were grouped into two. Group I (Study Group) were subjects with the clinical evidence along with one or more of the laboratory or radiological evidence for tuberculous meningitis. Group II (Control Group) comprised of subjects who were diagnosed to have CNS illness other than tuberculous menin...
متن کاملTuberculous meningitis: successful use of delayed corticosteroids in treatment and polymerase chain reaction in diagnosis.
The diagnosis of tuberculous meningitis remains an enigma despite recent technologic advances, such as computerized tomography (CT), magnetic resonance imaging (MRI), and more recently, polymerase chain reaction of the cerebrospinal fluid. We report a patient with tuberculous meningitis who, when treated with appropriate antitubercular medications, made no progress in her recovery. Approximatel...
متن کاملDiagnostic Value of Polymerase Chain Reaction for the Rapid Diagnosis of Clinically Suspected Tuberculous Meningitis
To study the efficiency of Polymerase Chain Reaction for the diagnosis of clinically suspected tuberculous meningitis, a rapid molecular technique was established. The conventional bacteriological methods rarely detect Mycobacterium tuberculosis in CSF and are of limited use in diagnosis of tuberculous meningitis (TBM). This double blind study was, therefore, directed to the molecular analysis ...
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ژورنال
عنوان ژورنال: Indian Journal of Pathology and Microbiology
سال: 2011
ISSN: 0377-4929
DOI: 10.4103/0377-4929.81610